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What is a Semaglutide Diet Plan for Weight Loss?

Andrea Jeffery, MS, RDN, LD , On September 20, 2024

Mealpro
What to eat when prescribed Semaglutide (Ozempic or Wegovy)

Semaglutide and GLP-1 Medications for Weight Loss

Semaglutide is a weight loss drug that mimics the natural peptide GLP-1, acting on brain receptors that control appetite. It suppresses hunger hormones, helping reduce food intake and overall daily calorie consumption. When in the bloodstream, semaglutide binds to receptors in the pancreas and brain, raising GLP-1 levels. This puts Semaglutide in the GLP-1 (also known as glucagon-like peptide-1) class of medications.

These medications originated to treat type 2 diabetes, and were later approved in the US for weight loss by the Food and Drug Administration (FDA) under Ozempic and Wegovy brand names.

Tirzepatide (1) is a different drug used for the same purpose as Semaglutide that has similar effects. The generic form can be found under the Mounjaro brand name.

Semaglutide is administered subcutaneously once a week and the dosage guidelines can vary between 1.7mg per week and 2.4mg per week.

Since Semaglutide is diabetes medication, the mechanism of action of semaglutide involves increasing sensitivity to insulin, which helps reduce overall circulating glucose and ultimately lowers the average blood sugar level.

To maximize the effectiveness of semaglutide for weight loss and ensure the greatest possible reduction in body weight, it is crucial to follow a semaglutide diet plan while using the drug.

Foods to Consume on a Semaglutide Diet Plan

When creating your semaglutide diet plan, incorporate non starchy vegetables, whole grains, nuts, protein foods, and legumes. See more about each below:

1. Non-Starchy Vegetables

These nutrient-dense foods are packed with fiber, essential vitamins, and minerals, providing numerous health benefits. Examples include leafy greens such as sautéed spinach, and cruciferous veggies like zucchini, spaghetti squash, riced cauliflower, as well as stuffed bell peppers, cucumber, tomatoes, and mushrooms.

squash can be enjoyed in a semaglutide diet plan

Spaghetti Squash is an ideal low calorie option

Eating non starchy vegetables can also help regulate blood sugar levels in those taking Wegovy, Ozempic or Mounjaro, reduce calorie intake, and promote satiety, which are all critical to successful chronic weight management and loss strategies.

2. Nuts

Nuts are recommended to be included in a semaglutide diet plan due to their high content of healthy fats, vitamins, minerals, fiber, and protein.

Nuts can be enjoyed in a semaglutide diet plan

Add nuts to your Semaglutide meals

Eating a handful of nuts daily improves the quality of your overall diet and promotes weight loss because they make you feel fuller with fewer calories for extended periods.

Nuts contain absorbable quality carbs, which help provide long-lasting energy throughout the day without spiking blood sugar levels quickly, as many other foods do. Adding more nutrient dense plant proteins and fatty foods such as almonds or walnut butter into a diet, has been linked with reducing inflammation levels which is crucial for maintaining weight loss progress while taking semaglutide medication.

3. Protein Foods

High protein foods, such as lean meats, fish, poultry, and tofu are important components of the semaglutide diet plan.
Examples include pan-seared swordfish, pan-seared salmon, shredded chicken breasts, and red meat, preferably with a lower fat content to limit saturated fats and plant-based sources like lentils or quinoa.

Salmon can be enjoyed in a semaglutide diet plan

Incorporate salmon in your Semaglutide diet plan

These foods provide energy and nutrients necessary for supporting daily metabolic functions. Foods high in protein support weight loss by using fat cells, decreasing hunger while providing essential amino acids, which are building blocks for the body’s muscle tissues.

4. Legumes

Legumes such as chickpeas, kidney beans, lentils, and sautéed spinach are recommended in a semaglutide diet plan. Legumes provide essential nutrients necessary for a healthy diet while on semaglutide.

Garbanzo beans

Garbanzo beans go great in a Semaglutide meal plan

They are an excellent plant protein, fiber, potassium, folate, zinc, and iron source. Legumes are low in fat while providing an optimized amount of proteins and vitamins.
As part of the vegetarian healthy lifestyle, meat eaters can leave room for some vegetables and incorporate legumes into their daily meal plans as sources of proteins, which tend to be leaner than animal-sourced ones.

5. Whole Grains

Whole grains are an important part of any diet plan as they help regulate blood sugar and satiety, and stabilize energy levels. Brown rice, oatmeal, quinoa, and even whole wheat bread have been proven to be excellent sources of carbohydrates that provide fiber and help reduce hunger cravings.

Salmon can be enjoyed in a semaglutide diet plan

Quinoa is a staple of whole grains

Whole grains are also excellent sources of vitamins, minerals, and essential nutrients like iron, zinc and calcium. They can significantly increase the body’s overall health by providing additional dietary protein for muscle growth.
Fiber content which helps with digestion and managing weight loss drug or gain due to overeating, are known to reduce the risk of diabetes and heart disease. Fruits and vegetables should also be incorporated, but incorporating regular servings of complex carbs vs simple carbs. The complex carbs from whole grain options is very beneficial for the diet plan for semaglutide users who want to lose weight, as it helps keep their hunger at bay while still maintaining a balanced nutrition intake every day to achieve healthy weight loss results.

Foods to Avoid on a Semaglutide Diet Plan

Avoid foods such as refined grains, foods with added sugar, fried foods, sugary drinks, and alcohol when on an Ozempec diet plan.

  • Refined Grains: These can aggravate semaglutide side effects. Eating these types of food can cause the blood sugar levels to spike quickly after meals, leading to cravings, heavy fatigue, and weight gain, all of which counteract the goal of taking this medication.

  • Sugar: Added sugars are found in many processed foods, such as candy, soda, baked goods, and packaged snacks, breakfast bars, granola cereals, energy drinks, and other sweetened beverages like juices or sodas. Their high levels of added sugar can contribute to weight gain, increase risk for developing type 2 diabetes, and lead to higher blood pressure and cholesterol.

  • Fried foods: These foods are high in saturated fat, trans fats, and calories that can worsen nausea, a common side effect of taking semaglutide or tirzepatide. Consuming greasy fried foods regularly will not support improved health and weight management while on medication. limit consumption of fried and greasy foods while using Wegovy, Ozempic or Mounjaro.

Summary of What the Best GLP-1/Semaglutide Diet Plan Should Be

A personalized Semaglutide diet plan is always best, but there are some guidelines to follow.

Semaglutide approved meals incorporate foods from all food groups. The semaglutide diet plan should focus on low-glycemic, nutrient-dense foods such as lean proteins, whole grains, non-starchy vegetables, and healthy fats. These ingredients support blood sugar regulation, promote satiety, and aid weight loss by mimicking hormones that boost insulin release. High-fiber foods are emphasized for digestive health and stable blood glucose levels.

great semaglutide diet plan

Chicken with Quinoa, Squash, and Yams

Portion Control & Balanced Nutrients: Meals should be appropriately portioned to manage calorie intake. Each meal provides a balance of macronutrients (proteins, carbohydrates, and fats) and micronutrients (vitamins and minerals). Here is the GLP-1 medication dietary guidelines:

  • Meals free from Refined Sugars: Avoid added sugars and opt for natural sweetness from fruits if needed.

  • Minimally Processed: Focus on whole, organic, and minimally processed ingredients.

  • Prioritize Lean Proteins: Focus On High-fiber foods & Whole Grains, Seek Non-Starchy Vegetables.

Why Choose MealPro’s Semaglutide Meal Plans?

Our ready made fitness meals are inherently healthy, and meet the general whole food, whole grain, high fiber, and high protein GLP-1 dietary recommendations.

What our team of experts has done, is to group a total of 15 entrees, and 4 breakfasts that can help you closely meet the dietary requirements to support the effectiveness of the GLP-1 medication.

MealPro’s semaglutide meal plan has the following benefits:

  • Tailored for GLP-1 needs: Whole foods, whole grains, high fiber, non-starch vegetables, cooked in olive or avocado oil, and high-quality proteins. Plant-based options also available.

  • Macronutrient balanced: Ensures consistent daily intake.

  • Delicious and varied: Unique flavors without the ‘diet’ feel.

  • Wide selection: Pick and choose your own meals week by week.

What Are Specifics About MealPro’s Meals Chosen for a Semaglutide Diet?

MealPro intends to provide an assortment of fitness meals for semaglutide that – if eaten 3 meals per day – can help individuals get close to (not achieve) the recommended dietary requirements.

Andrea Jeffery, MS, RDN, LD

Andrea holds a B.S in Dietetics and a Masters of Science in Nutrition from Idaho State University. She is a licensed dietitian through the Idaho State Board of Medicine. She is currently a MealPro blog contributor and serves as adjunct faculty at Idaho State University.